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KMID : 0881720090240010078
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Journal of Food Hygiene and Safety
2009 Volume.24 No. 1 p.78 ~ p.85
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The Effects of Extracts Mixture Drink from Inonotus Obliquus, Phellinus Linteus and Ganoderma Lucidum on Hematopoietic Stem Cells and Lymphocyte Subset of Blood in Human
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Bae Hyung-Suk
Kang Sung-Keun
Shin Il-Seob
Woo Sang-Kyu
Kim You-Joung
Kim Mi-Ae
Ra Jeong-Chan
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Abstract
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This study was performed to investigate the effect of extract mixture(IPGE) drink from Inonotus Obliquus, Phellinus Linteus and Ganoderma Lucidum on hematopoietic stem cells and lymphocyte subset[lymphocyte, CD4+ T cell, CD8+ T cell, Natural Killer(NK) cells] of blood in 37 participants who were healthy and about 40~70 years old. They were divided into two groups; extract mixture drink administration group(n=27) and placebo administration group(n=12). They were given the test drink daily for 4 weeks. Blood was obtained from the subjects every two week in the beginning of administration day to evaluate the CD34+ hematopoietic stem cells and immune cells. As results, CD34+ hematopoietic stem cells were significanly increased after taking IPGE drink for 4 weeks compared to that before taking the drink (p < 0.001). There was no significant changes in number of lymphocytes, CD4+ T cells, CD8+ T cells, NK cells and in the ratio of CD4+/CD8+ cell after taking the test drink. From these results, it was suggested that IPGE have a good health effect by promoting the proliferation of the hematopoietic stem cells.
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KEYWORD
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Inonotus Obliquus, Phellinus Linteus, Ganoderma Luciderm, Hematopoietic Stem Cells and Lymphocyte Subset
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